Overview of prognostic factors in adult gliomas

: Gliomas represent the majority of malignant central nervous system tumors, with most aggressive subtype, glioblastoma, accounting for almost 57% this entity. Type glioma and its incidence can vary depending on age presentation. In turn, outcomes significantly based actual type (histologically molecularly) patient, as well various tumor specific factors such size, location, comorbidities, etc. last decade we have been able to identify key molecular features that provided us greater insight into behavior these but spectrum treatment options remains limited. addition, ultimate causes death in patients gliomas are variable stochastic nature. Given complicated factors, prognostication extremely difficult. This review aims discuss low grade versus high gliomas, variability clinical poor prognosis, differences prognostic understanding between patients, caregivers, providers. We will also make some general recommendations where appropriate how approach subject from a palliative care perspective.