Overview of Complement Activation and Regulation

Complement activation, regulation, and molecular basis for complement-related diseases.

The complement system is an essential element of the innate immune response that becomes activated upon recognition of molecular patterns associated with microorganisms, abnormal host cells, and modified molecules in the extracellular environment. The resulting proteolytic cascade tags the complement activator for elimination and elicits a pro-inflammatory response leading to recruitment and ac...

Complement Activation and Regulation in Preeclamptic Placenta

Preeclampsia (PE) is a common disorder of pregnancy originating in the placenta. We examined whether excessive activation or poor regulation of the complement system at the maternal-fetal interface could contribute to the development of PE. Location and occurrence of complement components and regulators in placentae were analyzed. Cryostat sections of placentae were processed from 7 early-onset...

Regulation of complement by membrane proteins: an overview.

Complement System Part I – Molecular Mechanisms of Activation and Regulation

Complement is a complex innate immune surveillance system, playing a key role in defense against pathogens and in host homeostasis. The complement system is initiated by conformational changes in recognition molecular complexes upon sensing danger signals. The subsequent cascade of enzymatic reactions is tightly regulated to assure that complement is activated only at specific locations requiri...

a tripartite model of efl teachers attributions, burnout, and ‎self-regulation: towards the prospects of effective teaching

همطالعه حاضر به ارائه مدلی برای آموزش موثر زبان انگلیسی ‏می پردازد. مدل حاضر از سه عامل تاثیر گذار در کارایی ‏تدریس معلمان زبان انگلیسی بهره می برد. این سه عامل شامل ‏سبکهای اسنادی، خود تنطیمی و فرسودگی شغلی معلمان ایرانی ‏زبان انگلیسی می باشد. رساله مورد نظر درچهار فاز طراحی ‏شده است: فاز اول شامل طراحی و رواسازی پرسشنامه سبکهای ‏اسنادی معلمان زبان انگلیسی و فاز دوم شامل استفاده از ‏این پرسشنا...