Over-optimism in bioinformatics: an illustration

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Over-optimism in bioinformatics: an illustration

MOTIVATION In statistical bioinformatics research, different optimization mechanisms potentially lead to 'over-optimism' in published papers. So far, however, a systematic critical study concerning the various sources underlying this over-optimism is lacking. RESULTS We present an empirical study on over-optimism using high-dimensional classification as example. Specifically, we consider a 'p...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2010

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btq323