Outcomes of Allergy to Insect Stings in Children, With and Without Venom Immunotherapy

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منابع مشابه

Outcomes of Allergy to Insect Stings in Children, with and without Venom Immunotherapy

N Engl J Med 2004;351:668-74. Copyright © 2004 Massachusetts Medical Society. background Children are thought to “outgrow” the allergy to insect stings, but there are no reports documenting the natural history of this reaction. We studied the outcome of allergic reactions to insect stings in childhood 10 to 20 years afterward in patients who had not received venom immunotherapy and in those who...

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Outcomes of allergy to insect stings in children, with and without venom immunotherapy.

BACKGROUND Children are thought to "outgrow" the allergy to insect stings, but there are no reports documenting the natural history of this reaction. We studied the outcome of allergic reactions to insect stings in childhood 10 to 20 years afterward in patients who had not received venom immunotherapy and in those who had been treated. METHODS Between 1978 and 1985, we diagnosed allergic reac...

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Hymenoptera venom immunotherapy and field stings.

BACKGROUND Anaphylactic sting reactions in patients with Hymenoptera venom allergy are prevented by venom immunotherapy (VIT) in most patients. OBJECTIVE The aim of this study was to investigate re-sting reactions in the field during VIT or during an observation period of up to 13 years after cessation of treatment. Furthermore we sought to identify patients at higher risk of developing a sys...

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Allergy to insect stings. II. Phospholipase A: the major allergen in honeybee venom.

In order to determine the proteins of major allergenic importance in honeybee venom (Apis mellifera) it was chromatographed on G-50 Sephadex. The four major protein peaks eluted were identified as hyaluronidase, phospholipase, melittin, and apamin. Testing these preparations on the leukocytes of 6 honeybee-sensitive patients, with the in vitro method of histamine release, revealed that all indi...

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Stinging insect allergy: current perspectives on venom immunotherapy

Systemic allergic reactions to insect stings affect up to 5% of the population during their lifetime, and up to 32% of beekeepers. Such reactions can be fatal, albeit very rarely, and fear of a further systemic reaction (SR) can lead to significant anxiety and quality of life impairment. A recent Cochrane systematic review confirmed that venom immunotherapy (VIT) is an effective treatment for p...

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ژورنال

عنوان ژورنال: Pediatrics

سال: 2005

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.2005-0698hh