Outcomes and dose—volume parameters for computed tomography-based brachytherapy planning for vaginal recurrence of uterine cancer primarily treated with surgery

Background: This study aimed to evaluate the clinical outcomes and dose-volume parameters of computed tomography CT-based brachytherapy for vaginal recurrence uterine cancer after hysterectomy. Methods: We evaluated 22 patients treated with between December 2010 August 2015. Interstitial (ISBT) was used when tumor thicker than 5 mm and/or located at extended extravaginal tissue, whereas intercavitary performed if it or thinner. Results: Overall, 11 had cervical cancer, endometrial cancer. The median pretreatment size on magnetic resonance imaging 17 (range, 0–45 mm). Four recognized only in gynecological examination. primary location vagina, extension observed 9 patients. Seventeen (77%) received external beam radiotherapy brachytherapy. ISBT 12 (55%). target volume (CTV) D90 69.2 Gy (62.6–72.8 Gy). D2cc bladder, sigmoid, rectum were 70.2 (63.8–77.6), 37.4 (30.0–43.6), 52.8 (38.6–63.5 Gy), respectively. Complete response reached all 5-year overall survival rate local control (LC) 84.8 95.5%, No patient experienced grade ?3 complications. Conclusions: has potential become an essential treatment recurrences hysterectomy as can achieve good LC without increasing late complications selected less recurrences.