Osteosarcoma’s STAT-3 Vrs Kaempferia parviflora’s Compounds : Possible Drug Candidates

Osteosarcoma is a dominant type of bone cancer, associated with osteophytes (bone cells). Afflicts all age groups; generally manifesting in long bones human physiology(also other parts; including fine joints). Chemotherapy, surgery and radiation are the current therapeutics – uncertain results; often high degree failure; swift relapse; rebound aggression above debilitating post treatment out come conditions. In this investigation silico drug designing procedures have been used to predict natural compounds from Kaempferia parviflora (black ginger) as possible candidates for osteosarcoma. 8 its phyto-compounds (PCs) found be non-toxic also pass Lipinski’s rule 5 (@ 100%) vis-à-vis over expressed Signal Transducer And Activator Of Transcription 3(STAT3) protein dreaded All PCs indicate better binding affinity (greater likeness) than best popular allopathic Zoledronic acid (Toxic). offer good-excellent likeness. Alpha- Copaene (non Toxic) emerges Champion.