Osteoprotegerin Secretion by Mevastatin via p38MAPK and NF-kB
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چکیده
منابع مشابه
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In normal cells exposed to stress, the central transcription factor NF-kB is activated only transiently, to modulate the activation of downstream immune responses. However, in most cancers, NFkB is abnormally activated constitutively, contributing thus to oncogenesis and tumor progression. Therefore, downregulating NF-kBactivity is an important goal of cancer treatment. In order to control NF-k...
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ژورنال
عنوان ژورنال: Open Journal of Rheumatology and Autoimmune Diseases
سال: 2012
ISSN: 2163-9914,2164-005X
DOI: 10.4236/ojra.2012.22006