Osteoprotegerin levels in patients with severe mental disorders

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Osteoprotegerin levels in patients with severe mental disorders.

BACKGROUND Severe mental disorders are associated with elevated levels of inflammatory markers. In the present study, we investigated whether osteoprotegerin (OPG), a member of the tumour necrosis factor receptor family involved in calcification and inflammation, is elevated in patients with severe mental disorders. METHODS We measured the plasma levels of OPG in patients with severe mental d...

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Osteoprotegerin in Cardiometabolic Disorders

Osteoprotegerin (OPG), a glycoprotein traditionally implicated in bone remodelling, has been recently related to cardiovascular disease (CVD). Human studies show a positive relationship between circulating OPG, vascular damage, and CVD, and as such OPG has emerged as a potential biomarker for CVD. This review focuses on the relationship between circulating OPG and different endocrine cardiometa...

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ژورنال

عنوان ژورنال: Journal of Psychiatry and Neuroscience

سال: 2010

ISSN: 1488-2434

DOI: 10.1503/jpn.090088