Osteopenia in Growth Hormone (GH) Deficient Children: Effect of Growth Hormone Treatment
نویسندگان
چکیده
منابع مشابه
Growth hormone treatment in non-growth hormone-deficient children
Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD). With the availability of unlimited quantities of GH obtained from recombinant DNA technology, researchers started to explore new modalities to treat GHD children, as well as to treat a number of other non-GHD conditions. Although with so...
متن کاملNo Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment
It is still in doubt whether the standard-dose growth hormone (GH) used in Japan (0.5 IU/kg/week, 0.167 mg/kg/week) for growth hormone deficiency is effective for achieving significant adult height improvement in non-growth hormone deficient (non-GHD) short children. We compared the growth of GH-treated non-GHD short children with that of untreated short children to examine the effect of standa...
متن کاملOptimization of growth hormone therapy in growth hormone deficient children.
Successful treatment with human growth hormone (hGH) was initially reported by Raben in 19581. Although itis well established that pituitary derived or biosynthetic hGH increases the growth rate in growth hormone deficient children, many patients that were treated in the early days have not reached their target height, or attained adult height below the third percentile of population standards ...
متن کاملeffect of arginine infusion on ghrelin secretion in growth hormone-sufficient and gh-deficient children
background the physiological link between ghrelin and growth hormone (gh) has not yet been fully clarified. furthermore, the existence of a negative feedback mechanism between growth hormone–insulin-like growth factor (gh–igf)-i axis and ghrelin and the influence of amino acids on ghrelin secretion in children remain matters of debate. objectives to understand the regulation of ghrelin secretio...
متن کاملeffects of growth hormone replacement therapy on thyroid function tests in growth hormone deficient children
there are numerous, often contradictory reports on the effect of growth hormone (gh) therapy on thyroid function. these reports prompted us to evaluate the impact of gh therapy on thyroid function in previously euthyroid children with gh deficiency. twenty five clinically and biochemically euthyroid children with gh deficiency were studied. a thyroid profile (t4, free t4, t3 and tsh) was perfor...
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ژورنال
عنوان ژورنال: Clinical Pediatric Endocrinology
سال: 1994
ISSN: 0918-5739,1347-7358
DOI: 10.1297/cpe.3.supple5_204