Osmotic controlled drug delivery system (OSMO technology) and its impact on diabetes care
نویسندگان
چکیده
منابع مشابه
Osmotic Controlled Drug Delivery System: A Review
Department of Pharmaceutics, Hindu College of Pharmacy, Guntur, Andhra Pradesh, India. _______________________________________________________________________ ABSTRACT Conventional drug delivery systems have slight control over their drug release and almost no control over the effective concentration at the target site. This kind of dosing pattern may result in constantly changing, unpredictabl...
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Swellable-core technology (SCT) formulations that used osmotic pressure and polymer swelling to deliver drugs to the GI tract in a reliable and reproducible manner were studied. The SCT formulations consisted of a core tablet containing the drug and a water-swellable component, and one or more delivery ports. The in vitro and in vivo performance of two model drugs, tenidap and sildenafil, formu...
متن کاملControlled Drug Delivery System
Controlled release drug delivery systems provide uniform concentration of drug to the absorption site and thus allow the maintenance of plasma concentration within the therapeutic range which minimizes not only the side effects but also the frequency of administration. Oral Sustained release (SR) products provide an advantage over conventional dosage forms by optimizing properties of drugs in s...
متن کاملFormulation and Evaluation of Glibenclamide Osmotic Controlled Drug Delivery Systems
The objective of the study was to develop Controlled porosity and elementary osmotic pump-based drug delivery systems of Glibenclamide. The elementary osmotic pump (EOP) consists of an osmotic core with the drug surrounded by a semipermeable membrane drilled with a delivery orifice through which drug releases where as in controlled porosity osmotic pump drug release is accomplished by the use o...
متن کاملFormulation and Evaluation of Controlled Porosity Osmotic Drug Delivery System of Carvedilol Phosphate
Controlled porosity osmotic tablet of carvedilol phosphate prepared and evaluated in this study. Carvedilol phosphate is very low soluble drug. So it is difficult to formulate osmotic tablet of carvedilol phosphate which gives drug release up to 24 hr at zero order. To get desired dissolution profile various formulation parameters like osmogen concentration, level of weight gain and level of po...
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ژورنال
عنوان ژورنال: International Journal of Research in Medical Sciences
سال: 2020
ISSN: 2320-6012,2320-6071
DOI: 10.18203/2320-6012.ijrms20205861