Orthopedic Prosthetic Infections: Diagnosis and Orthopedic Salvage

Extended-Spectrum Beta-Lactamase Infections in Orthopedic-Related Devices and Prosthetic Joints.

Extended-spectrum beta-lactamase-producing Enterobacteriaceae have increasingly become a public health issue in a variety of infections, including urinary tract infections and postoperative infections. The complications that occur due to these organisms in bone, joint, and prosthetic joints have not been well defined. This study reviewed the clinical characteristics, risk factors, and outcomes ...

Persistence of bacterial DNA in orthopedic infections.

Polymerase chain reaction (PCR) has been proposed as a method to identify bacteria in clinical samples because it is more sensitive than culture techniques and can produce results rapidly. However, PCR can detect DNA from dead cells and thus cannot distinguish between live and dead cells in a tissue sample. Killed Staphylococcus aureus cells were implanted into the femurs and knee joints of rat...

Culture-Negative Infections in Orthopedic Surgery

Laboratory cultures are the main scientific input into the decisionmaking process that determines the course of treatment for suspected orthopedic infections, just as they constitute the mainstay of the diagnosis of infections in other medical specialties. This situation is archaic because culture techniques were virtually abandoned in Environmental Microbiology (Hugenholtz et al. 1998) many ye...

Peri-Prosthetic Infection in the Orthopedic Tumor Patient

Background: Infection complicates traditional joint reconstruction prostheses in up to 7% of cases, with even higher rates in oncologic cases. Questions / Purposes: The authors ask if prosthetic infection in bone tumor patients is associated with any epidemiologic, treatment, or outcome variables that could influence management of these difficult conditions. Patients and Methods: Authors retros...

Antibiotic-impregnated cement and beads for orthopedic infections.