Orlistat: weight lost at cost of HIV rebound
نویسندگان
چکیده
منابع مشابه
Orlistat and sibutramine beyond weight loss.
BACKGROUND AND AIM To investigate, through a meta-analysis of clinical trials, the effect of two weight-reducing drugs, such as orlistat and sibutramine, on serum lipid profiles in overweight and obese subjects, independently of weight loss. METHODS A systematic search strategy, incorporating the terms orlistat, sibutramine, fat, cholesterol, lipid profile, cardiovascular risk, was developed ...
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از منظر ریشه شناسی ، واژه "هرمنوتیک" به فرایند قابل درک و فهم نمودن شی، مفهوم یا موقعیتی مبهم وغیر قابل درک اشاره می کند.علم ترجمه، قلب علم هرمنوتیک محسوب می شود زیرا مارا از فاصله ها و تضاد هایی که در امر تاویل و تفسیر موجود است آگاه می سازد( پالمر، 1969). در حقیقت ، ترجمه را می توان نوعی تمرین دشوار هرمنوتیک دانست که متضمن درک معانی متون و انتقال وفادارانه این معانی و ساختارها از زبانی خاص با...
15 صفحه اولReview: orlistat and sibutramine are modestly effective for weight loss at 1 year.
and commentary also appear in ACP Journal Club. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . For correspondence: Dr R Padwal, University of Alberta and Walter C. Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada. rpadwal@ ualberta.ca Source of funding: no external funding. Orlistat (Orl) or sibutramine (Sib) ...
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Obesity is at epidemic proportions but treatment options remain limited. Treatment of obesity by calorie restriction (CR) despite having initial success often fails due to rebound weight gain. One possibility is that this reflects an increased body weight (BW) set-point. Indeed, high fat diets (HFD) reduce adult neurogenesis altering hypothalamic neuroarchitecture. However, it is uncertain if t...
متن کاملModeling and simulation of orlistat to predict weight loss and weight maintenance in obesity patients.
Orlistat is used clinically worldwide as anti-obesity drug. It is a chemically synthesized hydrogenated derivative of lipstatin and is an inhibitor of gastric and pancreatic lipases. It has been found to reduce the absorption of dietary fat in the gastrointestinal tract. Modeling and simulation based on pharmacokinetic/pharmacodynamic analysis is becoming increasingly used in the design of clin...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2016
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkw033