منابع مشابه
Phylogenetic Analysis of the Origin of the HIV virus
Acquired immunodeficiency syndrome (AIDS) is one of the most devastating epidemics. According to the report from the Centers for Disease Control and Prevention (CDC) at June 30, 1997, there were 612,078 cases of AIDS in the United States, and 379,258 deaths. Today, AIDS is the second leading killer of people aged 25 to 44 in the United States. The cause of AIDS is human immunodeficiency virus (...
متن کاملThe evolution of HIV-1 and the origin of AIDS.
The major cause of acquired immune deficiency syndrome (AIDS) is human immunodeficiency virus type 1 (HIV-1). We have been using evolutionary comparisons to trace (i) the origin(s) of HIV-1 and (ii) the origin(s) of AIDS. The closest relatives of HIV-1 are simian immunodeficiency viruses (SIVs) infecting wild-living chimpanzees (Pan troglodytes troglodytes) and gorillas (Gorilla gorilla gorilla...
متن کاملTracing the origin and history of the HIV-2 epidemic.
In this study we date the introduction of HIV-2 into the human population and estimate the epidemic history of HIV-2 subtype A in Guinea-Bissau, the putative geographic origin of HIV-2. The evolutionary history of the simian immunodeficiency virussooty mangabey/HIV-2 lineage was reconstructed by using available database sequences with known sampling dates, and a timescale for this history was c...
متن کاملOrigin and Epidemiological History of HIV-1 CRF14_BG
BACKGROUND CRF14_BG isolates, originally found in Spain, are characterized by CXCR4 tropism and rapid disease progression. This study aimed to identify the origin of CRF14_BG and reconstruct its epidemiological history based on new isolates from Portugal. METHODOLOGY/PRINCIPAL FINDINGS C2V3C3 env gene sequences were obtained from 62 samples collected in 1993-1998 from Portuguese HIV-1 patient...
متن کاملPhylogenetic studies on the origin of HIV-1
In 1999, Edward Hooper proposed that the human inmunodeficiency virus type 1 (HIV-1) could have originated in the bathes of live oral polio vaccine (OPV). He claimed that this vaccine was produced in chimpanzee kidney epithelial cell cultures rather than in monkey kidney cell cultures, as stated by the producers of OPV at the Winstar Institute in Philadelphia. The vaccine was applied to about o...
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ژورنال
عنوان ژورنال: BMJ
سال: 1989
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.298.6683.1267