منابع مشابه
Studies on Organogenesis
1. Isolated blood cells, when placed for incubation in a plasma substratum, are capable of constructing highly organized, tubular processes that project from the explanted cell mass into the surrounding medium. 2. The tubular structures have fibrillar walls that may be covered, eventually, by a membranous layer of leukocytes. Their lumina contain blood cells suspended in fluid. 3. The formation...
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In many animals, germ cells migrate to the gonad to assemble into a functional organ. Recent work in Drosophila has built a picture of the gene activities that specify the gonad and allow it to attract germ cells, and has led to the identification of a gene, columbus, that may encode the attractive factor.
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temporal coordination of numerous biomolecular interactions. Approaches geared toward elucidating the molecular and cellular basis of kidney development and branching morphogenesis have focused on the study of discrete molecules and signaling pathways by using genetic and in vitro approaches (reviewed in Refs. 11 and 71), more recently combined with microarray studies (66, 74, 75). To date, int...
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The recognition that lymphocytes existed in different varieties and that lymphoid organs were important for their differentiation greatly influenced immunological research. The growing awareness that started in the mid-fifties of the previous century has shifted the emphasis of immunology from a molecular, mostly serological science to the cell-oriented modern immunology of today. Matters such ...
متن کاملSimulating Organogenesis in COMSOL
Organogenesis is a tightly regulated process that has been studied experimentally for decades. Computational models can help to integrate available knowledge and to better understand the underlying regulatory logic. We are currently studying mechanistic models for the development of limbs, lungs, kidneys, and bone. We have tested a number of alternative methods to solve our spatiotemporal diffe...
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ژورنال
عنوان ژورنال: Chinese Medical Journal
سال: 2019
ISSN: 0366-6999
DOI: 10.1097/cm9.0000000000000048