Organic Synthesis at High Pressure. Efficient Ring Opening Reaction of Epoxides with Heterocycles.
نویسندگان
چکیده
منابع مشابه
Niobium Pentachloride Catalysed Ring Opening of Epoxides
Epoxide ring opening is a frequently required transformation in Organic Synthesis. In this paper we describe the application of NbCl5 for this purpose using three different substrates. Chlorohydrins, 1,2-diols, products containing solvent residues as well as rearrangement products are obtained, depending on both the substrate structure and reaction conditions. Rationalizations to account for so...
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For the first time B-podands have been studied as an efficient and powerful catalysts in the ring opening of epoxides with azide anion in water. The reaction afforded the corresponding 1,2-azidoalcohols with high regioselectivity under mild reaction conditions and in a highly atom economic fashion.
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ژورنال
عنوان ژورنال: THE REVIEW OF HIGH PRESSURE SCIENCE AND TECHNOLOGY
سال: 1998
ISSN: 0917-639X,1348-1940
DOI: 10.4131/jshpreview.7.1250