Orally Dosing Furosemide to Approximate Continuous Infusion
نویسندگان
چکیده
منابع مشابه
Continuous infusion vs. bolus dosing: implications for beta-lactam antibiotics.
Beta-lactam antibiotics display time-dependant pharmacodynamics whereby constant antibiotic concentrations rather than high peak concentrations are most likely to result in effective treatment of infections caused by susceptible bacteria. Continuous administration has been suggested as an alternative strategy, to conventional intermittent dosing, to optimise beta-lactam pharmacokinetic/pharmaco...
متن کاملDiuretic efficacy of high dose furosemide in severe heart failure: bolus injection versus continuous infusion.
OBJECTIVES The efficacy of high dose furosemide as a continuous infusion was compared with a bolus injection of equal dose in patients with severe heart failure. BACKGROUND The delivery rate of furosemide into the nephron has been proved to be a determinant of diuretic efficacy in healthy volunteers. METHODS In a randomized crossover study we compared the efficacy of a continuous infusion o...
متن کاملDiuretic Etficacy of High Dose Furosemide in Severe Heart Failure: Bolus Injection Versus Continuous Infusion
Objectives. The efficacy of high dose furosemide as a continuous infusion was compared with a bolus injection of equal dose in patients with severe heart failure. Background. The delivery rate of furosemide into the nephron has been proved to be a determinant of diuretic efficacy in healthy volunteers. Methods. In a randomized crossover study we compared the efficacy of a continuous infusion of...
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BACKGROUND Elevated intracranial pressure is one of the most common problems in patients with diverse intracranial disorders, leading to increased morbidity and mortality. Effective management for increased intracranial pressure is based mainly on surgical and medical techniques with hyperosmolar therapy as one of the core medical treatments. The study aimed to explore the effects of continuous...
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26 Despite the development of novel antibiotics active against Gram positive bacteria, 27 vancomycin generally remains the first treatment, although rapidly achieving concentrations 28 associated with maximal efficacy provides an unresolved challenge. The objective of this 29 study was to conduct a population pharmacokinetic analysis of vancomycin in a large 30 population of critically ill pati...
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ژورنال
عنوان ژورنال: The American Journal of Medicine
سال: 2017
ISSN: 0002-9343
DOI: 10.1016/j.amjmed.2017.03.052