Oral Transmucosal Fentanyl Citrate and Xerostomia
نویسندگان
چکیده
منابع مشابه
Oral transmucosal fentanyl citrate for cancer breakthrough pain: a review.
PURPOSE/OBJECTIVES To review the dose titration, efficacy, and safety of oral transmucosal fentanyl citrate (OTFC). DATA SOURCES Phase I and II clinical trial abstracts and evidence-based review articles. DATA SYNTHESIS OTFC has an onset, peak, and duration of action similar to that of an IV dose of an opioid and has been demonstrated to be effective and well tolerated for the management of...
متن کاملRampant caries from oral transmucosal fentanyl citrate lozenge abuse.
BACKGROUND Oral transmucosal fentanyl citrate lozenges (lollipops) are indicated for the oral management of breakthrough cancer pain. When abused, these sucrose-containing lozenges can cause rampant dental caries. CASE DESCRIPTION The authors examined a 19-year-old man whose dentist referred him because of total dental coronal destruction. After the authors questioned the patient, they conclu...
متن کاملInfluence of age on the pharmacokinetics and pharmacodynamics of oral transmucosal fentanyl citrate.
BACKGROUND Cancer pain is primarily a problem of older persons. Oral transmucosal fentanyl citrate (OTF) was developed to provide rapid analgesia and is the first drug specifically approved for treating breakthrough cancer pain. Fentanyl in OTF is absorbed across the oral mucosa but a considerable portion is swallowed and absorbed enterally. The effects of age on OTF pharmacokinetics and pharma...
متن کامل[Breakthrough pain frequency in cancer patients and the efficiency of oral transmucosal fentanyl citrate].
OBJECTIVES We aimed to search the frequency of breakthrough pain (BP) and the efficiency of oral transmucosal fentanyl citrate (OTFC) for the treatment of BP in cancer patients. METHODS One hundred twenty-four patients who had used strong opioid analgesics for more than one month were included in the study. The frequency of BP in those patients was determined. Fifty-two of the patients who de...
متن کاملOral transmucosal fentanyl citrate in cancer pain management: a practical application of nanotechnology
Pain is experienced by most cancer patients and represents an important issue in the clinical setting. Breakthrough pain is a transitory flare of pain that occurs in most cancer patients on a background of otherwise controlled persistent pain. Treatment of breakthrough pain is a challenging phenomenon. Oral transmucosal fentanyl citrate (OTFC; Actiq, Cephalon, UK), a new opioid formulation with...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pain and Symptom Management
سال: 2005
ISSN: 0885-3924
DOI: 10.1016/j.jpainsymman.2005.11.006