Oral Sustained Release of a Hydrophilic Drug Using the Lauryl Sulfate Salt/Complex

preparation and evaluation of zinc sulfate sustained release tablets using lipophilic and hydrophilic matrix

Hydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide

Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...

Hydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide

Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...

Formation of Nanoparticles of a Hydrophilic Drug using Supercritical CO2 and Microencapsulation for Sustained Release

The objective of this work was to develop sustained release formulation for hydrophilic drugs with minimal burst effects. For this purpose, nanoparticles of a hydrophilic drug were produced using supercritical CO2, which were then encapsulated into polymer microparticles using an anhydrous method, followed by studying their sustained in-vitro drug release. A hydrophilic drug, dexamethasone phos...

Clarithromycin Based Oral Sustained Release Nanoparticulate Drug Delivery System

The aim of the present work is to prepare and evaluate the oral mucoadhesive sustained release nanoparticles of clarithromycin in order to improve patient compliance by simplifing its administration, improving its therapeutic effect and reducing its dose related side effect. Clarithromycin containing gliadin nanoparticles were prepared by desolvation method using pluronic F-68 as a stabilizing ...