Oral Squamous Cell Carcinomas in Patient with Graft Versus-Host Disease Following Allogenic Bone Marrow Transplantation: A Case Report during Mutant COVID-19 Pandemic

Aplastic anaemia is a severe haematological disorder characterized by an inadequate number of hematopoietic stem cells, resulting in pancytopenia, formed hypocellular bone marrow. Disorders this nature are widely treated with haematopoietic cell transplantation (HSCT). A potential chronic complication following (HSCT) the growth secondary malignancies. Notably, patients suffering from graft versus host disease (cGvHD) to HSCT have been shown be more susceptible oral squamous carcinoma (OSCC). Here, we present rare case 30-year-old Libyan woman for aplastic anaemia, subsequent complications cGvHD and OSCC after few months HSCT. These carcinomatous lesions were detected buccal gingiva retromolar pad area at age 31. The report emphasizes connection between OSCC, appearance any time patient life. Thus, closer follow-up mandatory all who developed cGvHD, efficient prevention therapeutic approaches needed.