Oral premedication with pregabalin and clonidine for hemodynamic stability during laryngoscopy: a comparative study

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Clinical Investigation A Comparative Study of Oral Pregabalin and Clonidine for Attenuation of Hemodynamic Responses to Laryngoscopy and Tracheal Intubation

Background: Airway instrumentation by direct laryngoscopy and tracheal manipulation are powerful noxious stimuli causing adverse hemodynamic responses. This study evaluates and compares oral clonidine and pregabalin premedication on the hemodynamic responses following laryngoscopy and tracheal intubation and to assess the adverse events associated with these drugs. Materials & Methods: Sixty pa...

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Attenuation of hemodynamic responses following laryngoscopy and tracheal intubation -- comparative assessment of clonidine and gabapentin premedication.

OBJECTIVE The present study was conducted to compare the effect of clonidine and gabapentin premedication in modifying the hyperdynamic response following laryngoscopy and tracheal intubation. METHODS AND MATERIALS Seventy-five ASA I-II patients of both sexes (37 males (49.3%), 38 females (50.7%)) 18 to 45 years (mean 32.8 +/- 8.65 yr.) were randomly allocated into three equal groups (25 each...

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Premedication with oral clonidine decreases intraoperative bleeding and provides hemodynamic stability in cesarean section

BACKGROUND Intentional lowering of blood pressure helps to produce a desirably clean surgical field. Many drugs can be used to induce a hypotensive state, but due to their high potency and rapid effect, drugs that more easily and safely control the induction of hypotension are desirable. OBJECTIVES To investigate the effects of premedication with oral clonidine on intraoperative bleeding and ...

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premedication with oral clonidine decreases intraoperative bleeding and provides hemodynamic stability in cesarean section

background intentional lowering of blood pressure helps to produce a desirably clean surgical field. many drugs can be used to induce a hypotensive state, but due to their high potency and rapid effect, drugs that more easily and safely control the induction of hypotension are desirable. objectives to investigate the effects of premedication with oral clonidine on intraoperative bleeding and he...

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Effect of Premedication with Oral Clonidine on Hemodynamic Response during Electroconvulsive Therapy

BACKGROUND Electroconvulsive therapy (ECT) is the most effective treatment available for the acute treatment of depression in patients who do not respond to medications. It is generally used as a second line treatment for many psychological disorders, mainly major depression and schizophrenia where medication is not effective. ECT is often associated with some complications such as hypertension...

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ژورنال

عنوان ژورنال: International Journal of Basic & Clinical Pharmacology

سال: 2015

ISSN: 2319-2003

DOI: 10.5455/2319-2003.ijbcp20150423