Oral endotoxin in healthy adults

Pyrosequencing analysis of the oral microflora of healthy adults.

A good definition of commensal microflora and an understanding of its relation to health are essential in preventing and combating disease. We hypothesized that the species richness of human oral microflora is underestimated. Saliva and supragingival plaque were sampled from 71 and 98 healthy adults, respectively. Amplicons from the V6 hypervariable region of the small-subunit ribosomal RNA gen...

Occurrence of staphylococci in oral cavities of healthy adults and nasal-oral trafficking of the bacteria

Oral impact on daily performance in Iranian adults

BACKGROUND AND AIM: The aim of this study was to evaluate the prevalence and severity of oral impact on daily performance (OIDP) in adults attending dental clinics in the city of Kerman, Iran. METHODS: In 2010, a cross-sectional survey was conducted on a sample of 400 patients (age 20-50 years) referring to dental centers in Kerman. Validated OIDP inventory was used to collect data. Clinical ex...

Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults.

The pharmacokinetics, safety, and tolerability of posaconazole, an investigational triazole antifungal, were evaluated following the administration of rising single and multiple oral doses. A total of 103 healthy adults were enrolled in two phase I trials. Each study had a double-blind, placebo-controlled, parallel-group design with a rising single-dose (RSD) or rising multiple-dose (RMD) schem...

Vertebral Arteries in Healthy Adults

Background and Purpose To noninvasively estimate cerebral blood flow volume, a prospective study of color duplex sonography of the common, external, and internal carotid arteries and vertebral arteries of healthy adults was done. Cerebral blood flow was calculated with the sum of flow volumes in the internal carotid and vertebral arteries of both sides. Methods Using a 7.0-MHz linear transducer...