Optogenetic Activation of A11 Region Increases Motor Activity
نویسندگان
چکیده
منابع مشابه
Optogenetic activation of Gq signalling modulates pacemaker activity of cardiomyocytes.
AIMS Investigation of Gq signalling with pharmacological agonists of Gq-coupled receptors lacks spatio-temporal precision. The aim of this study was to establish melanopsin, a light-sensitive Gq-coupled receptor, as a new tool for the investigation of spatial and temporal effects of Gq stimulation on pacemaking in cardiomyocytes at an early developmental stage. METHODS AND RESULTS A vector fo...
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The manipulation of genetically targeted neurons with light (optogenetics) continues to provide unprecedented avenues into studying the function of the mammalian brain. However, potential translation into the clinical arena faces a number of significant hurdles, foremost among them the need for insertion of optical fibers into the brain to deliver light to opsins expressed on neuronal membranes...
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ژورنال
عنوان ژورنال: Frontiers in Neural Circuits
سال: 2018
ISSN: 1662-5110
DOI: 10.3389/fncir.2018.00086