منابع مشابه
Optimizing rational vaccine design
Amir Aharoni, Department of Life Sciences and the National Institute for Biotechnology in the Negev (NIBN), Ben-Gurion University, Beer-Sheva, Israel. The size of the microbial world is beyond our imagination. In last year’s crystal ball article, Tom Curtis compared the size of the microbial world to the size of the universe pointing out that the number of microorganisms in the world is billion...
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Live attenuated vaccine (LAV), mimicking natural infection, provides an excellent protection against microbial infection. The development of LAV, however, still remains highly empirical and the rational design of clinically useful LAV is scarcely available. Apoptosis and caspase activation are general host antiviral responses in virus-infected cells. Utilizing these tightly regulated host defen...
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So far, the development of a human immunodeficiency virus (HIV) vaccine has been unsuccessful. However, recent progress in the field of broadly neutralizing antibodies (bNAbs) has reinvigorated the search for an HIV vaccine. bNAbs develop in a minority of HIV infected individuals and passive transfer of these bNAbs to non-human primates provides protection from HIV infection. Studies in a numbe...
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ژورنال
عنوان ژورنال: Microbial Biotechnology
سال: 2009
ISSN: 1751-7915
DOI: 10.1111/j.1751-7915.2009.00090_7.x