Optimization of selection response under restricted inbreeding
نویسندگان
چکیده
منابع مشابه
Optimization under frequency-dependent selection.
We consider a model of frequency-dependent selection, which we refer to as the Wildcard Model. A variety of more specific models, representing quite diverse biological situations, are covered by the Wildcard Model as particular cases. Two very different particular models that are subsumed by the Wildcard Model are the game theoretically motivated two-phenotype model of Lessard [Lessard, S.,1984...
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Records of five inbred lines at the Livestock and Range Research Laboratory were used to evaluate effects of inbreeding and heterozygosity on preweaning traits. Members of each line were descendants of a single founder Hereford bull. A total of 8,065 records of birth weight and 7,380 records of preweaning daily gain and weaning weight were analyzed by derivative-free REML using a model that inc...
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A recent study has used inbreeding depression to gain insight into the maintenance of additive genetic variation in populations, with intriguing implications for good genes models of sexual selection.
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Inbreeding is often an inevitable outcome of strong directional artificial selection but on average it reduces population fitness with increased frequency of recessive deleterious alleles. Runs of homozygosity (ROH) representing genomic autozygosity that occur from mating between selected and genomically related individuals may be able to reveal the regions affecting fitness. To examine the inf...
متن کاملMaximizing the response of selection with a predefined rate of inbreeding: overlapping generations.
In a breeding scheme, the aim is high rates of genetic gain with limited inbreeding. A dynamic selection rule is developed that maximizes selection response in populations with overlapping generations. The rule maximizes the genetic merit of selected animals while limiting the average relationship of the population after the current round of selection. The latter is shown to limit the contribut...
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ژورنال
عنوان ژورنال: Genetics Selection Evolution
سال: 1990
ISSN: 1297-9686
DOI: 10.1186/1297-9686-22-1-93