Optimization of heterological expression of insulin receptor-related receptor ectodomain
نویسندگان
چکیده
منابع مشابه
Baculovirus-directed expression of the human insulin receptor and an insulin-binding ectodomain.
In this report we describe the use of the baculovirus expression system to overproduce the human insulin holoreceptor (HIR) and a truncated, secretory version of the HIR cDNA (HIRsec) consisting of the alpha subunit and the extracellular portion of the beta subunit (beta'). Sf9 cells infected with the full-length HIR viruses synthesize recombinant HIR (rHIR) with an insulin-binding alpha subuni...
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ژورنال
عنوان ژورنال: Доклады Академии наук
سال: 2019
ISSN: 0869-5652
DOI: 10.31857/s0869-56524851110-123