Optimization for ultra high pressure extraction of Scutellaria barbata by central composite design-response surface methodology

Optimization of ultrasonic extraction of alkaloids from Scutellaria barbata D. Don using response surface methodology

Based on a BoxBehnken design,response surface methodology was used to optimize the effects of processing parameters of extraction from Scutellaria barbata on total alkaloids yield. Three independent variables such as extraction time (X1), liquid-solid ratio (X2) and ultrasonic frequency (X3) were study. The P-value indicated that both extraction time (X1) and ultrasonic frequency (X3) had signi...

Preparation of Ultra High Molecular Weight Polyethylene Using Ziegler-Natta Catalyst System: Optimization of Parameters by Response Surface Methodology

Optimization of extraction process of hypericin from St. John’s Wort by central composite design-response surface methodology

The aim of present work was to find out the optimum combination of extraction process variables of hypericin from St. John’s wort, by revealing the mathematical functional relation of extraction temperature, ethanol concentration for the extraction yield, and to develop a validated HPLC method to determine hypericin in St. John’s wort extracts prepared. The HPLC separation was performed on a Lu...

Application of Central Composite Design for Optimization of Coacervative Extraction of Cu(II) Using Anionic Surfactant

The aim of this work was to develop a new and simple coacervative extraction method for the preconcentration and spectrophotometric determination of Cu(II) in water samples. Dithizone was used as the chelating agent while an anionic surfactant, namely sodium dodecyl sulfate (SDS), was used as extracting agent at room temperature. Central composite design (CCD) based on response surface methodol...

Response surface methodology for optimization of supercritical fluid extraction of orange peel essential oil

Background: Orange peel essential oils were obtained using supercritical fluid extraction. This method is an important high scaling extraction methods that used for extraction of plant and animal extracts. Methodology: The experimental parameters of SFE such as temperature, pressure, and extraction time and modifier volume were optimized using a central composite design after a 24-1fractional ...