OPTIMISATION OF IBUPROFEN FAST DISSOLVING TABLETS EMPLOYING STARCH XANTHATE USING 23 FACTORIAL DESIGN
نویسندگان
چکیده
منابع مشابه
Formulation and Optimization of Fast Dissolving Tablets of Olanzapine Using Vacuum Drying Technique by 2 Factorial Design
The purpose of this research was to develop fast dissolving tablets of olanzapine and to optimize the processing variables. Tablets containing olanzapine, camphor, crosscarmellose, and directly compressible lactose were prepared by direct compression technique. The tablets were compressed and later exposed to vacuum. Sublimation of camphor from tablets resulted in superior fast dissolving table...
متن کاملFast Dissolving Tablets – Future Aspects
Drug delivery system is an efficient tool for enhancing market, extending product life cycles and creating opportunities. Drug delivery system (DDS) makes a significant contribution to global pharmaceutical sales through market segmentation, and is moving rapidly[1]. Despite of tremendous innovations in drug delivery, the oral route remains the preferred route for administration of therapeutic ...
متن کاملDesign and Evaluation of Fast Dissolving Tablets of Clonazepam
In the present work, fast dissolving tablets of clonazepam were prepared by direct compression method with a view to enhance patient compliance. Three super-disintegrants, viz., crospovidone, croscarmellose sodium and sodium starch glycolate in different ratios with microcrystalline cellulose (Avicel PH-102) along with directly compressible mannitol (Pearlitol SD 200) to enhance mouth feel. The...
متن کاملFormulation Design and Optimization of Fast Dissolving Clonazepam Tablets
Fast dissolving tablets of clonazepam were prepared by direct compression method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of crospovidone and microcrystalline cellulose. Crospovidone (2-8% w/w) was used as superdisintegrant and microcrystalline cellulose (20-40% w/w) was used as di...
متن کاملFast Dissolving Tablets of Sertraline Hydrochloride
Sertraline Hydrochlride, the selective serotonin reuptake inhibitor (SSRI) is widely used in treatment of depression. Though Sertraline Hydrochloride is well absorbed after oral dosing, there is a first pass metabolism leading to a reduced bioavailability of the drug (44%). Therefore, the present investigation is concerned with the development of Fast Dissolving Tablets of Sertraline Hydrochlor...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2017
ISSN: 0975-7058
DOI: 10.22159/ijap.2017v9i5.19707