Optimal reference interval for homeostasis model assessment of insulin resistance in a Japanese population

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Optimal reference interval for homeostasis model assessment of insulin resistance in a Japanese population

The aim of the present study was to establish a reference interval for homeostasis model assessment of insulin resistance (HOMA-IR) in a Japanese population based on the C28-A3 document from the Clinical and Laboratory Standards Institute (CLSI). We selected healthy subjects aged 20-79 years, with fasting plasma glucose < 100 mg/dL, body mass index < 25 kg/m(2) and alanine aminotransferase < 31...

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Establishment of Reference Interval for Homeostasis Model Assessment of Insulin Resistance in Healthy Adult Males: a Pilot Study in Alexandria Governorate, Egypt

Abstract Objective: Homeostasis model assessment of insulin resistance (HOMA-IR) is a simple and practical method for estimation of insulin resistance (IR), but a reliable reference interval (RI) of HOMA-IR is needed to deduce the threshold level to define IR. This RI has been controversial in different populations and even more divergent when considering factors like age, gender and body mass...

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establishment of reference interval for homeostasis model assessment of insulin resistance in healthy adult males: a pilot study in alexandria governorate, egypt

abstract objective: homeostasis model assessment of insulin resistance (homa-ir) is a simple and practical method for estimation of insulin resistance (ir), but a reliable reference interval (ri) of homa-ir is needed to deduce the threshold level to define ir. this ri has been controversial in different populations and even more divergent when considering factors like age, gender and body mass ...

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Optimal cut‐off point for homeostasis model assessment of insulin resistance to discriminate metabolic syndrome in non‐diabetic Japanese subjects

We have recently established a 'health-associated' reference interval of homeostasis model assessment of insulin resistance (HOMA-IR) between 0.4 and 2.4. In the present study, the aim was to establish a 'decision-based' limit of HOMA-IR for the discrimination of metabolic syndrome (MetS) in non-diabetic Japanese subjects. The receiver-operating characteristic curve of HOMA-IR for detecting Met...

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Prediction of homeostasis model assessment of insulin resistance in Japanese subjects.

OBJECTIVE In our previous study, multivariate analysis showed that body mass index (BMI), triglycerides (TG) levels, and systolic blood pressure (SBP), in addition to fasting plasma glucose (FPG) levels, significantly correlated with homeostasis model assessment of insulin resistance (HOMA-IR). Our aim was to develop a predictive tool for HOMA-IR using tests of the specific health examinations....

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ژورنال

عنوان ژورنال: Journal of Diabetes Investigation

سال: 2011

ISSN: 2040-1116

DOI: 10.1111/j.2040-1124.2011.00113.x