Optimal ICSI timing after the first polar body extrusion in in vitro matured human oocytes

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Optimal ICSI timing after the first polar body extrusion in in vitro matured human oocytes.

BACKGROUND This study was conducted to investigate the fertilization and embryo development of human oocytes injected at different time intervals after extrusion of the first polar body (PB) following in vitro maturation (IVM) in IVM cycles. Also, we evaluated whether spindle imaging could serve as a tool to determine the optimal ICSI time. METHODS Oocytes were collected from 43 women with po...

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Background: The meiotic spindle plays an important role in the oocyte during chromosome alignment and separation at meiosis. The zona pellucid (ZP) is a dynamic matrix composed of filaments with the properties that might reflect the history of oocyte cytoplasmic maturation. Since, spindle and ZP in living oocytes are highly birefringent, their structures can be viewed noninvasively by using a P...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2007

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/dem124