Opticin Exerts Its Anti-angiogenic Activity by Regulating Extracellular Matrix Adhesiveness
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چکیده
منابع مشابه
Opticin Exerts Its Anti-angiogenic Activity by Regulating Extracellular Matrix Adhesiveness*
Opticin is an extracellular matrix glycoprotein that we identified associated with the collagen network of the vitreous humor of the eye. Recently, we discovered that opticin possesses anti-angiogenic activity using a murine oxygen-induced retinopathy model: here, we investigate the underlying mechanism. Using an ex vivo chick chorioallantoic membrane assay, we show that opticin inhibits angiog...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2012
ISSN: 0021-9258
DOI: 10.1074/jbc.m111.331157