Optical Imaging of Epileptiform Activity in Human Neocortex
نویسندگان
چکیده
منابع مشابه
Cholinergic modulation of epileptiform activity in the developing rat neocortex.
The effects of carbachol on picrotoxin-induced epileptiform activity and membrane properties of neurons in the developing rat neocortex were examined in an in vitro slice preparation. Intracellular recordings were obtained in layer II-III neurons of slices prepared from rats 9-21 days of age. Epileptiform activity in 9- to 14-day-olds consisted of a sharply rising, sustained (10-30 s) membrane ...
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The role of gamma-aminobutyric acid B (GABA(B)) receptors in the generation and maintenance of bicuculline-induced epileptiform activity in rat neocortical slices was studied using electrophysiological methods. A block of GABA(B) receptors in the presence of functional GABA(A) receptor-mediated inhibition was not sufficient to induce epileptiform activity. In the presence of the GABA(A) recepto...
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Waves of epileptiform activity in neocortex have three phenomenological stages: initiation, propagation, and termination. We use a well studied model of epileptiform activity in vitro to investigate directly the hypothesis that each stage is governed by an independent mechanism within the underlying cortical circuit. Using the partially disinhibited neocortical slice preparation, activity is in...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2004
ISSN: 0013-9580,1528-1167
DOI: 10.1111/j.0013-9580.2004.04010.x