منابع مشابه
Tissue optical immersion clearing.
In this article, we discuss the optical immersion method based on refractive index matching of scatterers (e.g., collagen, elastin fibers, cells and cell compartments) and the ground material (interstitial fluid and/or cytoplasm) of tissue and blood under the action of exogenous optical clearing agents. We analyze the optical clearing of fibrous and cell-structured tissues and blood from the po...
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BACKGROUND AND OBJECTIVE Light scattering from collagen within skin limits light-based therapeutics while increasing the risk of epidermal thermal injury. Specific chemicals show the ability to reduce light scattering by reversibly altering the optical properties of skin. This study examines the correlation between collagen solubility and the optical clearing potential (OCP) of sugars and sugar...
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Light scattering in biological tissues can be reduced by using optical clearing agents. Various physical methods in conjunction with agents have been studied to enhance the optical clearing efficacy of skin for diagnostic and therapeutic applications. In this study, we propose a new physical method to enhance the optical clearing potential of topically applied glycerol. A microneedle roller is ...
متن کاملFunctional imaging in bulk tissue specimens using optical emission tomography: fluorescence preservation during optical clearing.
Optical emission computed tomography (optical-ECT) is a technique for imaging the three-dimensional (3D) distribution of fluorescent probes in biological tissue specimens with high contrast and spatial resolution. In optical-ECT, functional information can be imaged by (i) systemic application of functional labels (e.g. fluorophore labelled proteins) and/or (ii) endogenous expression of fluores...
متن کاملOptical clearing of tissues and cells.
In the visible and near-infrared wavelength range, the maority of tissues and blood are low absorbing but highly scatering media. Scattering defines spectral and angular characeristics of light interacting with living objects, as well as its enetration depth. Thus, the deleterious effects of the optical roperties of tissues and blood on light-based diagnostic and herapeutic techniques may be ef...
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ژورنال
عنوان ژورنال: BIO-PROTOCOL
سال: 2014
ISSN: 2331-8325
DOI: 10.21769/bioprotoc.1042