منابع مشابه
Tissue optical immersion clearing.
In this article, we discuss the optical immersion method based on refractive index matching of scatterers (e.g., collagen, elastin fibers, cells and cell compartments) and the ground material (interstitial fluid and/or cytoplasm) of tissue and blood under the action of exogenous optical clearing agents. We analyze the optical clearing of fibrous and cell-structured tissues and blood from the po...
متن کاملOptical clearing of tissues and cells.
In the visible and near-infrared wavelength range, the maority of tissues and blood are low absorbing but highly scatering media. Scattering defines spectral and angular characeristics of light interacting with living objects, as well as its enetration depth. Thus, the deleterious effects of the optical roperties of tissues and blood on light-based diagnostic and herapeutic techniques may be ef...
متن کاملRevisiting optical clearing with dimethyl sulfoxide (DMSO).
Functional optical characterization of disease progression and response to therapy suffers from loss of spatial resolution and imaging depth due to scattering. Here we report on the ability of dimethyl sulfoxide (DMSO) alone to reduce the optical scattering of skin. We observed a threefold reduction in the scattering of skin with topical DMSO application. With an in vivo window chamber model, w...
متن کاملCollagen solubility correlates with skin optical clearing.
Biomedical optics and photomedicine applications are challenged by the turbidity of most biological tissue systems. Nonreactive, biocompatible chemical agents can induce a reversible reduction in optical scattering of collagenous tissues such as human skin. Herein we show that a chemical agent's tissue optical clearing potential is directly related to its collagen solubility, providing a ration...
متن کاملRecent progress in tissue optical clearing
Tissue optical clearing technique provides a prospective solution for the application of advanced optical methods in life sciences. This paper gives a review of recent developments in tissue optical clearing techniques. The physical, molecular and physiological mechanisms of tissue optical clearing are overviewed and discussed. Various methods for enhancing penetration of optical-clearing agent...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Advances in Optical Technologies
سال: 2008
ISSN: 1687-6393,1687-6407
DOI: 10.1155/2008/267867