منابع مشابه
Opioids for neuropathic pain.
BACKGROUND The use of opioids for neuropathic pain remains controversial. Studies have been small, have yielded equivocal results, and have not established the long-term risk-benefit ratio of this treatment. OBJECTIVES To assess the efficacy and safety of opioid agonists for the treatment of neuropathic pain. SEARCH STRATEGY We searched the Cochrane Central Register of Controlled Trials (2n...
متن کاملOpioids and neuropathic pain.
Opioids are broad spectrum analgesics that may be beneficial to alleviate the intense perception of algesia in patients suffering with pain. They have been one of the most controversial analgesics, in part because of their potential for addiction. Opioids or any currently available analgesic will not provide effective analgesia for every patient with chronic neuropathic pain (NP), but overall o...
متن کاملOpioids and chronic neuropathic pain.
Chronic neuropathic pain is a serious problem resulting from injury to the central or peripheral nervous system; it affects more than 2 million Americans. Despite advances in our understanding of the pathophysiology and molecular biology of neuropathic pain, its clinical management remains disappointing and controversial. Antidepressants and anticonvulsants have been demonstrated to provide ana...
متن کاملOpioids for chronic nonmalignant and neuropathic pain.
It is now two hundred years ago that theGerman pharmacist F.W. Sertürner isolated the first pure opium alkaloid (Sertürner, 1805, 1806, 1817) that he named ‘‘morphine’’. Up-to-now the later so-called opioids are still the mainstay in modern pharmacological treatment of acute and chronic pain. Driven by the growing awareness of an unacceptably widespread undertreatment of pain together with the ...
متن کاملOpioids for chronic noncancer pain
The number of available opioid preparations, each with differing chemical properties, structure and opioid receptor affinity, increases with time. The efficacy of these opioids in the treatment of pain arising from a diverse range of disorders is beyond question. With the passage of time, the list of those conditions where an opioid is recommended as a treatment option increases, and that list ...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2013
ISSN: 1465-1858
DOI: 10.1002/14651858.cd006146.pub2