Opioids for Breakthrough Cancer Pain
نویسندگان
چکیده
منابع مشابه
A Comprehensive Review of Rapid-Onset Opioids for Breakthrough Pain
Breakthrough pain (BTP) is a transitory pain (reaching maximum severity in ~15 minutes and lasting ~60 minutes in patients with cancer) that occurs despite the management of chronic pain with long-term around-the-clock analgesia. BTP occurs in 33-65% of patients with chronic cancer pain and in ~70% of patients with chronic noncancer pain. BTP has historically been managed with short-acting opio...
متن کاملThe use of rapid onset opioids for breakthrough cancer pain: the challenge of its dosing.
Breakthrough cancer pain (BTcP) has been defined as a transitory increase in pain intensity on a baseline pain of moderate intensity in patients on analgesic treatment regularly administered. This review provides updated information about the use of opioids for the treatment of BTcP, with special emphasis on the use of new rapid onset opioids (ROOs). Due to its slow onset to effect oral opioids...
متن کاملTransdermal opioids for cancer pain
Patients with moderate to severe malignancy-related pain frequently require the use of opioid pharmacotherapy. Unfortunately, many cancer patients continue to be prescribed subtherapeutic doses of pain medications resulting in undo suffering and diminished quality of life. The choice of analgesic pharmacotherapy should be individualized and based on the intensity and etiology of pain reported b...
متن کاملAn economic evaluation of short-acting opioids for treatment of breakthrough pain in patients with cancer.
OBJECTIVE Breakthrough cancer pain (BTCP) represents a considerable economic burden. A decision-analysis model was developed to evaluate the cost-effectiveness of intranasal fentanyl spray (INFS) compared with oral transmucosal fentanyl citrate (OTFC) and fentanyl buccal tablet (FBT) for the treatment of BTCP. METHODS The model was parameterized for Sweden to estimate the costs and benefits a...
متن کاملEfficacy of intranasal fentanyl spray versus other opioids for breakthrough pain in cancer.
OBJECTIVE To compare the efficacy of intranasal fentanyl spray (INFS), oral transmucosal fentanyl citrate (OTFC), fentanyl buccal tablet (FBT) and oral morphine (OM) for the treatment of breakthrough cancer pain (BTCP). METHODS A systematic literature review (Medline, EMBASE, BIOSIS; 1996-2007) identified six randomised controlled trials (RCTs) investigating the effects of INFS, OTFC, FBT and...
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ژورنال
عنوان ژورنال: The Oncologist
سال: 2020
ISSN: 1083-7159,1549-490X
DOI: 10.1634/theoncologist.2020-0280