Opioid Treatment Patterns Following Prescription of Immediate-Release Hydrocodone
نویسندگان
چکیده
منابع مشابه
Patterns of abuse and routes of administration for immediate‐release hydrocodone combination products
PURPOSE Prescriptions for hydrocodone immediate-release (IR) combination products have recently decreased, yet they represent the majority of opioid prescriptions dispensed and are commonly abused analgesics among both adults and adolescents. Little data exist to understand the contribution of IR products to the problem of prescription opioid abuse. This study aimed to better understand abuse p...
متن کاملSingle- and multiple-dose pharmacokinetics of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (MNK-155) compared with immediate-release hydrocodone bitartrate/ibuprofen and immediate-release tramadol HCl/acetaminophen
OBJECTIVE To characterize the single-dose and steady-state pharmacokinetics (PK) of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (IR/ER HB/APAP), IR HB/ibuprofen, and IR tramadol HCl/APAP. METHODS In this single-center, open-label, randomized, four-period crossover study, healthy participants received four treatments under fasted conditions: 1) a single dos...
متن کاملComparison of single-dose and multiple-dose pharmacokinetics between two formulations of hydrocodone bitartrate/acetaminophen: immediate-release versus biphasic immediate-release/extended release
OBJECTIVE This study aimed to compare the single-dose and steady-state pharmacokinetics (PK) of biphasic immediate-release (IR)/extended-release (ER) hydrocodone bitartrate (HB)/acetaminophen (APAP) and IR HB/APAP. SETTING The study was conducted in a contract research center. PARTICIPANTS The study included healthy adults. INTERVENTIONS In a three-way crossover study, Study 1, participan...
متن کاملPatterns of prescription opioid abuse and comorbidity in an aging treatment population.
Very little is known about the impact of age and gender on drug abuse treatment needs. To examine this, we recruited 2,573 opioid-dependent patients, aged from 18 to 75 years, entering treatment across the country from 2008 to 2010 to complete a self-administered survey examining drug use histories and the extent of comorbid psychiatric and physical disorders. Moderate to very severe pain and p...
متن کاملExtended-release hydrocodone – gift or curse?
Hydrocodone is a semisynthetic opioid, which has been used for decades as a short-acting analgesic combined with acetaminophen (or less commonly ibuprofen). Several long-acting, non-acetaminophen-containing hydrocodone formulations are undergoing trials in the US under the auspices of the US Food and Drug Administration, and may be available shortly. This article reviews some of the advantages ...
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ژورنال
عنوان ژورنال: Journal of Managed Care & Specialty Pharmacy
سال: 2016
ISSN: 2376-0540,2376-1032
DOI: 10.18553/jmcp.2016.22.4.358