Opioid endocrinopathy: A clinical problem in patients with cancer pain
نویسندگان
چکیده
منابع مشابه
Opioid-induced endocrinopathy.
Debilitating chronic nonmalignant pain is often managed using opioid medications. However, with increased use of this drug class comes concern about adverse effects on patients' endocrine function. In the present review, the authors discuss opioid-induced interference with the hypothalamic-pituitary-gonadal axis, effects on adrenal androgen production, and endocrine deficiency. In addition, the...
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Introduction: Because of not applying analgesics in mastectomy candidates and the complications of analgesic therapy in these patients on the one hand and increased pain intensity in patients who undergo mastectomy following radiotherapy on the other hand, the present study aimed to evaluate foot reflexology massage on pain and the need for opioids in breast cancer patients undergoing mastectom...
متن کاملClinical Implications of Opioid Pharmacogenomics in Patients With Cancer.
BACKGROUND Pain can be a significant burden for patients with cancer and may have negative effects on their quality of life. Opioids are potent analgesics and serve as a foundation for pain management. The variation in response to opioid analgesics is well characterized and is partly due to genetic variability. METHODS We reviewed the results of clinical studies to evaluate the relationships ...
متن کاملعنوان : Effect of Spiritual Care on Pain of Breast Cancer Patients: A Clinical Trial
چکیده: Background: One of the most important symptoms and complications of breast cancer is pain with an extensive impact on life dimensions, management of which requires comprehensive nursing care and interventions. Given that spiritual care is an essential and unique part of care and spirituality is an indispensable part of man's life, we aimed to determine the effect of spiritual care in bre...
متن کامل[Interindividual variation of pharmacokinetic disposition of and clinical responses to opioid analgesics in cancer pain patients].
Use of prescription opioids for cancer pain according to the World Health Organization analgesic ladder has been accepted in Japan. Although oxycodone and fentanyl are commonly used as first-line analgesics, a few clinical reports have been published on interindividual variations in their pharmacokinetics and clinical responses in cancer patients. (1) Some factors relating to CYP2D6, CYP3A, ATP...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2016
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2016.3156