Oocyte donation for stem cell research

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Oocyte donation for stem cell research.

The future success of stem cell research by means of somatic cell nuclear transfer (SCNT) depends on a sufficient supply of human oocytes. However, oocyte donation presents certain risks for the donor, and concerns for women's welfare are rightly vocalized. At the same time, these risks are comparable with the risks faced by other healthy research subjects. Thus, research donation can withstand...

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Proposed oocyte donation guidelines for stem cell research.

To expand the availability of stem cell lines suitable for basic research and clinical application, somatic cell nuclear transfer has been proposed and will require human oocyte donation. The recommendations made by the California Institute of Regenerative Medicine advisory committee on oocyte donation are based on peer-reviewed, best practices, and best clinical judgment and are intended to as...

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Oocyte Donation: an Overview

The use of donor oocytes has expanded the scope of assisted reproductive technology (ART) for women with poor oocyte quantity and quality. In vitro fertilisation with oocyte donation (IVF-OD) is considered to give better implantation, pregnancy, and livebirth rates compared to IVF with autologous oocytes. Maternal age, infertility factors, BMI, smoker status, and ethnicity reduce reproductive o...

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Implications of oocyte cryostorage for the practice of oocyte donation.

As the efficiency of oocyte cryopreservation has increased rapidly in recent years, oocytes are currently being stored either in the course of IVF treatments or as a fertility preservation measure. These practices may have an impact on the number of available donor oocytes due to two different dynamics: first, a certain percentage of women for whom oocytes were cryopreserved will eventually not...

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A cost-effectiveness comparison of embryo donation with oocyte donation.

OBJECTIVE To compare the cost-effectiveness of embryo donation (ED) to that of oocyte donation (OD). DESIGN Calculation of cost-effectiveness ratios (costs per outcome achieved) using data derived from clinical practices. SETTING In vitro fertilization centers and embryo donation programs. PATIENT(S) Infertile couples undergoing oocyte donation or embryo donation. INTERVENTION(S) Oocyte...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2006

ISSN: 1460-2350,0268-1161

DOI: 10.1093/humrep/del431