Onychomycosis: local pharmacokinetics and the future of topical antifungals
نویسندگان
چکیده
منابع مشابه
Pharmacokinetics and pharmacodynamics of antifungals.
Application of pharmacodynamic principles to antifungal drug therapy of Candida and Aspergillus infections has provided and understanding of the relationship between drug dosing and treatment efficacy. Observations of the pharmacodynamics of triazoles and AmB have correlated with the results of clinical trials and have proven useful for validation of in vitro susceptibility breakpoints. Althoug...
متن کاملTopical antifungals for seborrhoeic dermatitis
BACKGROUND Seborrhoeic dermatitis is a chronic inflammatory skin condition that is distributed worldwide. It commonly affects the scalp, face and flexures of the body. Treatment options include antifungal drugs, steroids, calcineurin inhibitors, keratolytic agents and phototherapy. OBJECTIVES To assess the effects of antifungal agents for seborrhoeic dermatitis of the face and scalp in adoles...
متن کاملOnychomycosis: rationalization of topical treatment.
BACKGROUND Fungal infection of the nail affects millions of people worldwide and has an estimated prevalence of more than 10% of the general population. OBJECTIVES To determinate the prevalence of fungal infection in toenails, in order to decide the treatment policy for onychomycosis. METHODS We evaluated 331 patients with suspected clinical toenail onychomycosis affecting at least two toen...
متن کاملساختار کلاسهایی از حلقه های z- موضعی و c- موضعی the structure of some classes of z-local and c-local rings
فرض کنیمr یک حلقه تعویض پذیر ویکدار موضعی باشدو(j(r رایکال جیکوبسن r و(z(r مجموعه مقسوم علیه های صفر حلقه r باشد.گوییم r یک حلقه z- موضعی است هرگاه j(r)^2=. .همچنین برای یک حلقه تعویض پذیر r فرض کنیم c یک عنصر ناصفر از (z( r باشد با این خاصیت که cz( r)=0 گوییم حلقه موضعی r یک حلقه c - موضعی است هرگاه و{0 و z(r)^2={cو z(r)^3=0, نیز xz( r)=0 نتیجه دهد که x عضو {c,0 } است. در این پایان نامه ساخ...
Onychomycosis: Potential of Nail Lacquers in Transungual Delivery of Antifungals
Onychomycosis constitutes the most common fungal infection of the nail (skin beneath the nail bed) that affects the finger as well as toe nails. It is an infection that is initiated by yeasts, dermatophytes, and nondermatophyte molds. Nail lacquers are topical solutions intended only for use on fingernails as well as toenails and have been found to be useful in the treatment of onychomycosis. T...
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ژورنال
عنوان ژورنال: Immunopathology, Allergology, Infectology
سال: 2016
ISSN: 2412-320X
DOI: 10.14427/jipai.2016.2.78