Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts.
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چکیده
منابع مشابه
Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts.
The conversion of cells from a normal phenotype to full malignancy apparently requires multiple genetic events. Efforts to reconstruct multistep tumorigenesis in cell culture have shown that two types of oncogenes (typified by HRAS and MYC) can cooperate to elicit complete transformation. Transformation of embryonic rodent cells by single oncogenes is reputed either not to occur or to require s...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1988
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.85.12.4355