On the Etiology of Keratocyte Loss during Contact Lens Wear

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On the etiology of keratocyte loss during contact lens wear.

PURPOSE To employ confocal microscopy to investigate the etiology of keratocyte loss after short-term contact lens wear by monitoring quantitative changes in keratocyte density. METHODS Twenty neophyte subjects aged 26 +/- 3 years participated in the study, which was conducted over the course of three experimental sessions. In the first session, one eye of each subject was fitted with a silic...

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BACKGROUND Keratocytes are specialised, rapidly moving cells that generate substantial contractile force perpendicular to their direction of locomotion. Potential roles for contractile force in cell motility include cell-body transport, regulation of adhesion, and retraction of the cell's trailing edge. RESULTS To investigate contact dynamics, we used simultaneous confocal fluorescence and in...

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2004

ISSN: 1552-5783

DOI: 10.1167/iovs.04-0129