منابع مشابه
The role of sialic acid synthases in sialic acid biosynthesis
Introduction The sialic acids comprise a diverse family of nine-carbon keto-sugars, the majority of which are structural derivatives of neuraminic acid (Fig. 1). Neuraminic acid has an amino moiety at the C-5 position, and carboxylate at C-2 which confers negative charge at physiological pH. Whereas unsubstituted neuraminic acid is not known to exist in nature, over 40 substituted variations (c...
متن کاملFluorometric Assay of Sialic Acid in Brain Gangliosides.
In pursuing quantitative histochemical investigations aimed at demonstrating the biochemical architecture of human frontal cortex (l-4), we found it necessary to determine ganglioside sialic acid in submicrogram amounts. Even when adapted to the microscale, spectrophotometric methods lack the sensitivity required for studying nervous tissue samples containing less than 0.3 pg of sialic acid. Si...
متن کاملSialic acid tissue distribution and influenza virus tropism
Avian influenza A viruses exhibit a strong preference for using alpha2,3-linked sialic acid as a receptor. Until recently, the presumed lack of this receptor in human airways was believed to constitute an efficient barrier to avian influenza A virus infection of humans. Recent zoonotic outbreaks of avian influenza A virus have triggered researchers to analyse tissue distribution of sialic acid ...
متن کاملAssessment of Sialic Acid Distribution in Mouse Epididymis
Previous studies have shown that epididymal epithelium and its secretions are critical for sperm maturation. These secretions contain many glycoconjugates with sialic acid terminal sugar. This terminal sugar by interveining in cellular interactions and masking surface receptors, has an important role in sperm maturation and protection. Moreover lectins have been employed as useful probes to det...
متن کاملEffect of ellagic acid on thiol levels in different brain tissue in an animal model of Parkinson's disease
Background & Aim: Parkinson's disease (PD) can be created with loss of dopaminergic substantial nigra neurons which is widely associated with oxidative stress and reduced glutathione (GSH), as the most important and abundant thiol in tissues and one of the antioxidant defense, is one of the earliest biochemical events related to Parkinson's and consumption of antioxidants has a protective effec...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1956
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.10-0694