On gallic acid

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Gallic acid

Anhydrous 3,4,5-trihy-droxy-benzoic acid, C(7)H(6)O(5), is essentially planar, with its non-H atoms exhibiting mean and maximum deviations from coplanarity of 0.014 and 0.0377 (5) Å, respectively. The C-C-C-OH torsion angle about the bond linking the carboxyl group to the benzene ring is -0.33 (10)°. In the crystal, the -COOH groups form centrosymmetric hydrogen-bonded cyclic dimers [graph set ...

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Gallic acid pyridine monosolvate

IN THE TITLE COMPOUND (SYSTENATIC NAME: 3,4,5-trihy-droxy-benzoic acid pyridine monosolvate), C(5)H(5)N·C(7)H(6)O(5), the gallic acid mol-ecule is essentially planar (r.m.s deviation = 0.0766 Å for non-H atoms) and is linked to the pyridine mol-ecule by an O-H⋯N hydrogen bond. An intra-molecular O-H⋯O hydrogen bond occurs in the gallic acid mol-ecule. The gallic acid and pyridine mean planes ma...

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Different generation of inhibitors against gallic acid-induced apoptosis produces different sensitivity to gallic acid.

Gallic acid (3,4,5-trihydroxybenzoic acid), a naturally occurring plant phenol, showed selective cytotoxicity against tumor cells with higher sensitivity than normal cells such as hepatocytes and keratinocytes. To elucidate the difference in sensitivity between normal and tumor cells to gallic acid, we studied whether the inhibitor of gallic acid-induced apoptosis existed or not. A serum-free c...

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The inhibitory activity of gallic acid against DNA methylation: application of gallic acid on epigenetic therapy of human cancers

Epigenome aberrations have been observed in tobacco-associated human malignancies. (-)-epigallocatechin-3-gallate (EGCG) has been proven to modulate gene expression by targeting DNA methyltransferases (DNMTs) through a proposed mechanism involving the gallate moiety of EGCG. We show that gallic acid (GA) changes the methylome of lung cancer and pre-malignant oral cell lines and markedly reduces...

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Encapsulation of gallic acid/cyclodextrin inclusion complex in electrospun polylactic acid nanofibers: Release behavior and antioxidant activity of gallic acid.

Cyclodextrin-inclusion complexes (CD-ICs) possess great prominence in food and pharmaceutical industries due to their enhanced ability for stabilization of active compounds during processing, storage and usage. Here, CD-IC of gallic acid (GA) with hydroxypropyl-beta-cyclodextrin (GA/HPβCD-IC) was prepared and then incorporated into polylactic acid (PLA) nanofibers (PLA/GA/HPβCD-IC-NF) using ele...

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ژورنال

عنوان ژورنال: The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science

سال: 1837

ISSN: 1941-5966,1941-5974

DOI: 10.1080/14786443708649283