Omental Gangrene and Porto-Mesenteric Thrombosis in a Patient of Protein C and Protein S Deficiency

Protein C deficiency and mesenteric venous thrombosis.

A 22-year-old woman with a history of gestational toxicosis and oral contraceptive use for 3 years reported progressive vague abdominal pain and vomiting over a 2-day period, without constipation, followed by rectal bleeding. On physical examination in the emergency department, the patient was afebrile, her blood pressure was 110/70 mm Hg and her pulse rate was 80 beats/min. There was diffuse a...

Portal and mesenteric thrombosis revealing constitutional protein C deficiency.

: the effect of sericin levels (silk glue protein) on rate of in vitro maturation, fertilization and culture of sheep oocytes

هدف از آزمایش اول بررسی اثر سطوح مختلف سریسین [0 (control), 0.1, 0.5, 1.0, 2.5 %] افزوده شده به محیط , ivm بر cumulus cell expansion، بلوغ هسته و توسعه متوالی جنین، در گوسفندان نژاد سنجابی در فصل تولید مثلی می باشد. از سرگیری میوز به وسیله خارج شدن اولین پولار بادی اندازه گیری و هم چنین درصد رسیدن جنین های دو سلولی به مرحله کلیواژ و بلاستوسیت نیز به عنوان نشانه ای از میزان شایستگی توسعه اولیه ج...

Mesenteric venous thrombosis in protein S deficiency: case report and literature review.

A 3 1-year-old woman presented with a two day history of sudden onset severe constant epigastric pain associated with nausea and coffee-grounds vomiting. She had a long history of heartburn treated by her general practitioner with intermittent omeprazole. There was no history of melaena, peptic ulcer or gallstone disease. However she had had pulmonary embolism postpartum six years before and ha...

Protein C and protein S deficiency - practical diagnostic issues.

Protein C (PC) and protein S (PS) are vitamin K-dependent glycoproteins, that act as natural anticoagulants. The proteolytic activation of PC by thrombin occurs on the surface of endothelial cells and involves thrombomodulin and endothelial PC receptor. In the presence of PS, phospholipids and calcium, activated PC (APC) inactivates membrane bound factors V (FVa) and FVIIIa by their cleavage at...