Oligoclonal bands in cerebrospinal fluids: significance of corresponding bands in serum for diagnosis of multiple sclerosis.
نویسندگان
چکیده
منابع مشابه
Oligoclonal bands in cerebrospinal fluids: significance of corresponding bands in serum for diagnosis of multiple sclerosis.
Controversy exists regarding the definition of oligoclonal bands in cerebrospinal fluid (CSF) and whether CSF bands with corresponding bands in the serum should be disregarded in the interpretation. Much of this controversy results from not distinguishing between the sensitivities of different techniques used for these studies. Because the combination isoelectric focusing/silver staining is mor...
متن کاملReibergram and oligoclonal bands in diagnosis of multiple sclerosis.
INTRODUCTION In this study authors have analyzed the correlation between the IgG immunoglobulins in cerebrospinal fluid and the findings of oligoclonal bands on gel. Immunoglobulin IgG in cerebrospinal fluid (CSF) can be detected in neurological diseasses (infections and inflammatory neurological diseases and in demyelinating diseases, like multiple sclerosis (MS)). Quantitative IgG in CSF can ...
متن کاملCSF -- oligoclonal bands in multiple sclerosis.
The present paper is concerned with a correlation between clinical parameters of multiple sclerosis and different agar gel electrophoretical patterns in CSF. The agar gel electrophoresis represents clearly the most sensitive method for the demonstration of oligoclonal bands in CSF.
متن کاملMore on oligoclonal bands and diagnosis of multiple sclerosis.
A When we consider that creatinine and uric acid, for example, are excreted in concentrations of about 15 and 5 mmoLfL, we can already observe positive biases caused by these interferencesat a sample:reagent volume ratio of 1:5 (1). However, this ratio does not yet permit measurement of microalbuminuria. Thus, the interferingreactions of urinary components with bromphenol blue preclude use of t...
متن کاملThe significance of serum oligoclonal bands in neurological diseases.
The presence of oligoclonal bands (OCBs) of immunoglobulin G (IgG) in CSF provides evidence for the occurrence of a humoral immune response, but it is not always appreciated that the oligoclonal IgG may have originated in the serum. To determine the diagnostic significance of serum OCBs 146 patients with serum OCBs were identified among 1874 patients with suspected neurological disorders (7.6%)...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1988
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/34.4.764