Olfactory ensheathing cells in facial nerve regeneration

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The migration of olfactory ensheathing cells during development and regeneration.

The primary olfactory nervous system is unique in that it continuously renews itself and regenerates after injury. These properties are attributed to the presence of olfactory glia, termed olfactory ensheathing cells (OECs). Evidence is now emerging that individual OEC populations exist with distinct anatomical localisations and physiological properties, but their differential roles have not be...

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Transplanted olfactory ensheathing cells promote regeneration of cut adult rat optic nerve axons.

Transplantation of olfactory ensheathing cells into spinal cord lesions promotes regeneration of cut axons into terminal fields and functional recovery. This repair involves the formation of a peripheral nerve-like bridge in which perineurial-like fibroblasts are organized into a longitudinal stack of parallel tubular channels, some of which contain regenerating axons enwrapped by Schwann-like ...

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Protective effect of adult olfactory ensheathing cells against 6-OHDA toxicity in PC-12 cells

Olfactory ensheathing cells (OEC) have been successfully used to stimulate the growth of injured fibers and to promote functional recovery within the injured adult CNS. These cells exhibit functional properties, which are known to be involved in axonal elongation. OEC express high level of growth factors including NGF, GDNF, BDNF and NT-3, which are known to play an important role in nerve rege...

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Protective effect of adult olfactory ensheathing cells against 6-OHDA toxicity in PC-12 cells

Olfactory ensheathing cells (OEC) have been successfully used to stimulate the growth of injured fibers and to promote functional recovery within the injured adult CNS. These cells exhibit functional properties, which are known to be involved in axonal elongation. OEC express high level of growth factors including NGF, GDNF, BDNF and NT-3, which are known to play an important role in nerve rege...

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CNPase Expression in Olfactory Ensheathing Cells

A large body of work supports the proposal that transplantation of olfactory ensheathing cells (OECs) into nerve or spinal cord injuries can promote axonal regeneration and remyelination. Yet, some investigators have questioned whether the transplanted OECs associate with axons and form peripheral myelin, or if they recruit endogenous Schwann cells that form myelin. Olfactory bulbs from transge...

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ژورنال

عنوان ژورنال: Brazilian Journal of Otorhinolaryngology

سال: 2020

ISSN: 1808-8694

DOI: 10.1016/j.bjorl.2018.07.006