Oleanolic acid and hederagenin from the stems ofCephalaria transsylvanica
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چکیده
منابع مشابه
Pharmacology of oleanolic acid and ursolic acid.
Oleanolic acid and ursolic acid are triterpenoid compounds that exist widely in food, medicinal herbs and other plants. This review summarizes the pharmacological studies on these two triterpenoids. Both oleanolic acid and ursolic acid are effective in protecting against chemically induced liver injury in laboratory animals. Oleanolic acid has been marketed in China as an oral drug for human li...
متن کاملOleanolic acid ethanol monosolvate
CRYSTALS OF THE TITLE COMPOUND (SYSTEMATIC NAME: 3β-hy-droxy-olean-12-en-28-oic acid ethanol monosolvate), C(30)H(48)O(3)·C(2)H(5)OH, were obtained from unsuccessful co-crystallization trials. The asymmetric unit contains two symmetry-independent oleanolic acid mol-ecules, as well as two ethanol solvent mol-ecules. Inter-molecular O-H⋯O hydrogen bonds stabilize the crystal packing. In the olean...
متن کاملIsolation and Quantificative Analysis of Oleanolic Acid from Satureja mutica Fisch. & C. A. Mey.
Background: Satureja mutica (Lamiaceae) is an herbaceous plant which grows in North-West of Iran. Oleanolic acid has been previously isolated from some Lamiaceae genus and showed a broad range of biological activities. Besides Silphium spp., Panax quinquefolium root and Calendula officinalis flower as the interesting source of oleanolic acid used in the herbal industry, here we report the iso...
متن کاملAntidiabetogenic activity of oleanolic acid glycosides from medicinal foodstuffs.
Oleanolic acid glycosides from several medicinal foodstuffs were found to show potent inhibitory activity on the increase of serum glucose levels in oral glucose-loaded rats. By examination of the structure-activity relationships, the 3-O-glucuronide moiety and the 28-carboxyl group in oleanolic acid glycosides were required to exert the hypoglycemic activity. Oleanolic acid glycosides were fou...
متن کاملEnhancement of Platelet Aggregation by Ursolic Acid and Oleanolic Acid
The pentacyclic triterpenoid ursolic acid (UA) and its isomer oleanolic acid (OA) are ubiquitous in food and plant medicine, and thus are easily exposed to the population through natural contact or intentional use. Although they have diverse health benefits, reported cardiovascular protective activity is contentious. In this study, the effect of UA and OA on platelet aggregation was examined on...
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ژورنال
عنوان ژورنال: Chemistry of Natural Compounds
سال: 1976
ISSN: 0009-3130,1573-8388
DOI: 10.1007/bf00564988