Olanzapine produced a higher clinical response rate than risperidone in schizophrenia
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چکیده
منابع مشابه
Clinical trial response and dropout rates with olanzapine versus risperidone.
BACKGROUND In schizophrenia, comparing treatment dropouts between olanzapine and risperidone can be useful to better understand their relative effectiveness. OBJECTIVE To analyze the differences in the rates of dropout from clinical trials and response between these 2 antipsychotics. METHODS Literature search was based on MEDLINE (1966-May 2002). Analysis 1 included 4 randomized studies (83...
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Oxidative stress has been suggested to contribute to the pathophysiology of schizophrenia. Increased oxidative stress is the result of either an increased production of free radicals or a depletion of the endogenous antioxidants. However, whether this imbalance of oxidant-antioxidant status in schizophrenia is integral to disease itself or the effect of antipsychotic drugs is not clearly unders...
متن کاملOlanzapine versus risperidone. A prospective comparison of clinical and economic outcomes in schizophrenia.
OBJECTIVE To compare the clinical and economic outcomes associated with olanzapine and risperidone treatment for schizophrenia. DESIGN AND SETTING An international, multicentre, double-blind, prospective study. To facilitate economic comparisons, our sample was restricted to patients enrolled in US sites. 150 patients with a Diagnostic and Statistical Manual of mental disorders, 4th edition (...
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OBJECTIVE This study prospectively examined the effectiveness of treatment with olanzapine versus risperidone in reducing violent behavior among patients with schizophrenia under "usual care" conditions in the community. METHOD Participants were 124 adults with DSM-IV-diagnosed schizophrenia-spectrum disorders receiving services in public-sector mental health systems in North Carolina. After ...
متن کاملOlanzapine has poorer efficacy than risperidone for the treatment of the negative symptoms of schizophrenia
1. Yaqub M, Ismail S, Babiker S, Sathyanarayana Rao TS. Psychiatrists’ responsibilities with regards to patients’ fitness to drive. Indian J Psychiatry 2016;58:287-90. 2. Roy S, Dasgupta A, Banerjee U, Chowdhury P, Mukhopadhyay A, Saha G, et al. Role of membrane cholesterol and lipid peroxidation in regulating the Na+/K+-ATPase activity in schizophrenia. Indian J Psychiatry 2016;58:317-25. 3. G...
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ژورنال
عنوان ژورنال: Evidence-Based Mental Health
سال: 1998
ISSN: 1362-0347
DOI: 10.1136/ebmh.1.2.55