Off-label use of atypical antipsychotics- Where are we?

Introduction Nowadays, In the exercise of psychiatric clinical activity, prescription atypical antipsychotics is a widespread practice. However, despite approval in treatment psychoses and bipolar affective disorder, where its effectiveness clearly demonstrated, these drugs are off-label prescribed most situations. Objectives This work aims to clarify which frequent conditions their more common. Methods Bibliographic research Pubmed® database using terms “atypical use” Results According scientific literature consulted, may represent about 70% total psychotropic drugs. Risperidone, olanzapine, quetiapine aripiprazole among antipsychotics. The often addictive disorders, anxiety post-traumatic stress personality eating insomnia dementia, therapeutic benefits demonstrated when carefully selected. Conclusions can be interpreted from two points view. On one hand, it guide innovation practice improve symptoms patients who do not respond standard treatments. other associated with negative consequences due lack data on safety efficacy Despite prescribing antipsychotics, there no evidence-based recommendation beyond disorder. Thus, prescribed, we must proceed careful monitoring consider risks relation prescription. Disclosure Interest None Declared