Ocular changes with oral and transepidermal diethylcarbamazine therapy of onchocerciasis.
نویسندگان
چکیده
منابع مشابه
Further studies on the treatment of ocular onchocerciasis with diethylcarbamazine and suramin.
The purpose of the present study was to determine whether or not the elimination of microfilariae by diethylcarbamazine citrate (DEC) would reduce the side effects of a subsequent course of suramin and thus make it more acceptable and safer in the treatment of onchocerciasis. Fifty-four heavily infected patients with ocular onchocerciasis were treated with an initial 2-week course of DEC, in wh...
متن کاملOcular onchocerciasis.
ONCHOCERCIASIS is caused by infection with the adult filarial worm Onchocerca volvulus; the microfilariae of this worm develop in the body of man and sometimes penetrate the tissues of the eye where they set up pathological changes leading to blindness; embryos may also be found in the skin, in lymph glands, in the fluid of hydroceles, and in effusions into joints. The disease has been reported...
متن کاملDeseril and diethylcarbamazine in the treatment of onchocerciasis.
SIR-We have previously experienced great difficulty in using diethylcarbamazine (dec) for the treatment of heavily infected patients in Cameroon (FUGLSANG & ANDERSON, 1974; ANDERSON et al., 1976). SALAZARMALLEN (personal communication) believes that an injection of Deseril (Sandoz) alleviates the initial adverse effects of dec in the skin and conjunctiva, and thus makes the use of this drug mor...
متن کاملOcular lesions of onchocerciasis.
THIS paper aims at describing, illustrating, and interpreting the ocular lesions associated with onchocerciasis. The literature of onchocerciasis already includes many pictures of the ocular lesions. The paintingst and diagrams in this paper supplement those previously published and are intended to fill gaps in the existing literature. The accompanying text expresses the author's views on the i...
متن کاملChanges in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
Eighteen patients, moderately to heavily infected with onchocerciasis, were treated with a standard course of diethylcarbamazine citrate (DEC-C). In addition to the well recognised systemic reactions to treatment, the following ocular changes occurred during therapy: (1) Transient pigment epithelial lesions were detected in 7 patients by fluorescein angiography. (2) Optic disc leakage, as shown...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1981
ISSN: 0007-1161
DOI: 10.1136/bjo.65.7.494